gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase EC#: 4.3.2.6; ChemWhat Code: 1382875

Product Name gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase
Example Structure Example Structure of gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase EC#: 4.3.2.6
Synonyms btrG, gamma-glutamyl cyclotransferase, GGC
EC Number 4.3.2.6
CAS Registry Number
Comments The enzyme catalyses the last step in the biosynthesis of the aminoglycoside antibiotic butirosin B. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the ¦Á-amine of the terminal ¦Ã-L-glutamate of the side chain, releasing it as the cyclic 5-oxoproline.
Cofactor
History
Reactions Gamma-L-glutamyl-butirosin B = butirosin b + 5-oxoproline.

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