gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase EC#: 4.3.2.6; ChemWhat Code: 1382875
| Product Name | gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase |
| Example Structure |  |
| Synonyms | btrG, gamma-glutamyl cyclotransferase, GGC |
| EC Number | 4.3.2.6 |
| CAS Registry Number | |
| Comments | The enzyme catalyses the last step in the biosynthesis of the aminoglycoside antibiotic butirosin B. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the ¦Á-amine of the terminal ¦Ã-L-glutamate of the side chain, releasing it as the cyclic 5-oxoproline. |
| Cofactor | |
| History | |
| Reactions | Gamma-L-glutamyl-butirosin B = butirosin b + 5-oxoproline. |
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