GDP-L-colitose synthase EC#: 1.1.1.356; ChemWhat Code: 1373475
| Product Name | GDP-L-colitose synthase |
| Example Structure |  |
| Synonyms | |
| EC Number | 1.1.1.356 |
| CAS Registry Number | |
| Comments | The enzyme is involved in biosynthesis of L-colitose, a 3,6-dideoxyhexose found in the O-antigen of Gram-negative lipopolysaccharides, where it catalyses the reaction in the reverse direction. The enzyme also performs the NAD(P)H-dependent epimerisation at C-5 of the sugar. The enzyme from Yersinia pseudotuberculosis is Si-specific with respect to NAD(P)H [1]. |
| Cofactor | |
| History | |
| Reactions | GDP-beta-L-colitose + NAD(P)(+) = GDP-4-dehydro-3,6-dideoxy-alpha-D- mannose + NAD(P)H. |
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