Product Name
glucosinolate gamma-glutamyl hydrolase
Example Structure
Synonyms
At4g30530, gamma-glutamyl peptidase 1, gamma-glutamyl peptidase 3, GGP1, GGP3
EC Number
3.4.19.16
CAS Registry Number
Comments
This enzyme, characterized from the plant?Arabidopsis thaliana, participates in the biosynthesis of the plant defense compounds glucosinolates and camalexin. It is the only known plant enzyme capable of hydrolysing the ¦Ã-glutamyl residue of glutathione in the cytosol.
Cofactor
History
Reactions
(1) An S-((1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl)-L- glutathione + H(2)O = an S-((1E)-1-(hydroxyimino)-omega- (methylsulfanyl)alkyl)-L-cysteinylglycine + L-glutamate. (2) (E)-1-(glutathion-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H(2)O = (E)-1-(glycylcystein-S-yl)-2-(1H-indol-3-yl)acetohydroximate + L-glutamate. (3) 2-(glutathion-S-yl)-2-(1H-indol-3-yl)acetonitrile + H(2)O = 2-(glycylcystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + L-glutamate. (4) (Z)-1-(glutathion-S-yl)-2-phenylacetohydroximate + H(2)O = (Z)-1- (glycylcystein-S-yl)-2-phenylacetohydroximate + L-glutamate.
