glutamate synthase (NADH) EC#: 1.4.1.14; ChemWhat Code: 1374268

Product Name glutamate synthase (NADH)
Example Structure Example Structure of glutamate synthase (NADH) EC#: 1.4.1.14
Synonyms gltA, GltA2, gltB, glutamate (reduced nicotinamide adenine dinucleotide) synthase, glutamate synthase, glutamate synthase (NADH), glutamate synthase (NADH-dependent), glutamate synthetase, glutamine 2-oxoglutarate aminotransferase, GOGAT, L-glutamate synthase (NADH), L-glutamate synthetase, NADH glutamate synthase, NADH-dependent glutamate synthase, NADH-dependent glutamine-2-oxoglutarate aminotransferase, NADH-GltS, NADH-glutamate synthase, NADH-GOGAT, NADH-GOGAT I, NADH-GOGAT II, NADH-GOGAT1, NADH-GOGAT2, NADH: GOGAT, synthase, glutamate (reduced nicotinamide adenine dinucleotide)
EC Number 1.4.1.14
CAS Registry Number 65589-88-0
Comments A flavoprotein (FMN). The reaction takes place in the direction of L-glutamate production. The protein is composed of two domains, one hydrolysing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2, glutaminase), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2, glutamate dehydrogenase).
Cofactor FMN
History
Reactions 2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + Nadh.

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