glutaminyl-peptide cyclotransferase EC#: 2.3.2.5; ChemWhat Code: 1377147
| Product Name | glutaminyl-peptide cyclotransferase |
| Example Structure | ![]() |
| Synonyms | AtQC, cyclotransferase, glutaminyl-transfer ribonucleate, DromeQC, gamma-glutamylamine cyclotransferase, GGACT, glutamine cyclotransferase, glutaminyl cyclase, glutaminyl-tRNA cyclotransferase, Golgi-resident glutaminyl cyclase, gQC, h-isoQC, isoDromeQC, isoQC, QC, QCT, Qpct, Qpct1, sQC, StQC |
| EC Number | 2.3.2.5 |
| CAS Registry Number | 37257-21-9 |
| Comments | Involved in the formation of thyrotropin-releasing hormone and other biologically active peptides containing N-terminal pyroglutamyl residues. The enzyme from papaya also acts on glutaminyl-tRNA. |
| Cofactor | |
| History | |
| Reactions | L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH(3). |
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