glutaryl-CoA dehydrogenase (acceptor) EC#: 1.3.99.32; ChemWhat Code: 1374236

Product Name glutaryl-CoA dehydrogenase (acceptor)
Example Structure Example Structure of glutaryl-CoA dehydrogenase (acceptor) EC#: 1.3.99.32
Synonyms GDH, GDHDes, glutaryl-CoA dehydrogenase (non-decarboxylating), glutaryl-coenzyme A dehydrogenase, nondecarboxylating glutaryl-coenzyme A dehydrogenase, nondecarboxylating, glutaconyl-coenzyme A-forming GDH
EC Number 1.3.99.32
CAS Registry Number
Comments The enzyme contains FAD. The anaerobic, sulfate-reducing bacterium Desulfococcus multivorans contains two glutaryl-CoA dehydrogenases: a decarboxylating enzyme (EC 1.3.8.6), and a nondecarboxylating enzyme (this entry). The two enzymes cause different structural changes around the glutaconyl carboxylate group, primarily due to the presence of either a tyrosine or a valine residue, respectively, at the active site.
Cofactor FAD
History
Reactions Glutaryl-CoA + acceptor = (E)-glutaconyl-CoA + reduced acceptor.

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