glutathione amide-dependent peroxidase EC#: 1.11.1.17; ChemWhat Code: 1374847

Product Name glutathione amide-dependent peroxidase
Example Structure Example Structure of glutathione amide-dependent peroxidase EC#: 1.11.1.17
Synonyms garB, More, Prx-containing peroxidase, Prx/Grx chimeric enzyme
EC Number 1.11.1.17
CAS Registry Number
Comments This enzyme, which has been characterized from the proteobacterium Marichromatium gracile, is a chimeric protein, containing a peroxiredoxin-like N-terminus and a glutaredoxin-like C terminus. The enzyme has peroxidase activity towards hydrogen peroxide and several small alkyl hydroperoxides, and is thought to represent an early adaptation for fighting oxidative stress [1]. The glutathione amide disulfide produced by this enzyme can be restored to glutathione amide by EC 1.8.1.16 (glutathione amide reductase).
Cofactor
History
Reactions 2 glutathione amide + H(2)O(2) = glutathione amide disulfide + 2 H(2)O.

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