glutathione amide reductase EC#: 1.8.1.16; ChemWhat Code: 1374688

Product Name glutathione amide reductase
Example Structure Example Structure of glutathione amide reductase EC#: 1.8.1.16
Synonyms GAR, garB
EC Number 1.8.1.16
CAS Registry Number
Comments A dimeric flavoprotein (FAD). The enzyme restores glutathione amide disulfide, which is produced during the reduction of peroxide by EC 1.11.1.17 (glutathione amide-dependent peroxidase), back to glutathione amide (it catalyses the reaction in the opposite direction to that shown). The enzyme belongs to the family of flavoprotein disulfide oxidoreductases, but unlike other members of the family, which are specific for NADPH, it prefers NADH [1].
Cofactor FAD
History
Reactions 2 glutathione amide + NAD(+) = glutathione amide disulfide + Nadh.

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