glutathione-specific gamma-glutamylcyclotransferase EC#: 4.3.2.7; ChemWhat Code: 1382876
| Product Name | glutathione-specific gamma-glutamylcyclotransferase |
| Example Structure |  |
| Synonyms | CHAC, CHAC1, CHAC2, gamma-GCG, GCG1, RipAY, RSp1022, YER63c |
| EC Number | 4.3.2.7 |
| CAS Registry Number | |
| Comments | The enzyme, found in bacteria, fungi and animals, is specific for glutathione (cf. EC?4.3.2.9, ¦Ã-glutamylcyclotransferase). The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the ¦Á-amine of the?L-glutamyl residue, releasing it as the cyclic 5-oxo-L-proline. |
| Cofactor | |
| History | |
| Reactions | Glutathione = L-cysteinylglycine + 5-oxo-L-proline. |
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