glutathione-specific gamma-glutamylcyclotransferase EC#: 4.3.2.7; ChemWhat Code: 1382876

Product Name glutathione-specific gamma-glutamylcyclotransferase
Example Structure Example Structure of glutathione-specific gamma-glutamylcyclotransferase EC#: 4.3.2.7
Synonyms CHAC, CHAC1, CHAC2, gamma-GCG, GCG1, RipAY, RSp1022, YER63c
EC Number 4.3.2.7
CAS Registry Number
Comments The enzyme, found in bacteria, fungi and animals, is specific for glutathione (cf. EC?4.3.2.9, ¦Ã-glutamylcyclotransferase). The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the ¦Á-amine of the?L-glutamyl residue, releasing it as the cyclic 5-oxo-L-proline.
Cofactor
History
Reactions Glutathione = L-cysteinylglycine + 5-oxo-L-proline.

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