glycerophospholipid arachidonoyl-transferase (CoA-independent) EC#: 2.3.1.147; ChemWhat Code: 1376940

Product Name glycerophospholipid arachidonoyl-transferase (CoA-independent)
Example Structure Example Structure of glycerophospholipid arachidonoyl-transferase (CoA-independent) EC#: 2.3.1.147
Synonyms Acyltransferase, 1-alkylglycerophosphocholine, CoA-independent transacylase, CoA-IT, CoAIT, Coenzyme A-independent transacylase
EC Number 2.3.1.147
CAS Registry Number 102347-79-5
Comments Catalyses the transfer of arachidonate and other polyenoic fatty acids from intact choline or ethanolamine-containing glycerophospholipids to the sn-2 position of a lyso-glycerophospholipid. The organyl group on sn-1 of the donor or acceptor molecule can be alkyl, acyl or alk-1-enyl. The term ‘radyl’ has sometimes been used to refer to such substituting groups. Differs from EC 2.3.1.148 glycerophospholipid acyltransferase (CoA-dependent) in not requiring CoA and in its specificity for poly-unsaturated acyl groups.
Cofactor
History
Reactions 1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso- sn-glycero-3-phosphoethanolamine = 1-organyl-2-arachidonoyl-sn-glycero-3- phosphoethanolamine + 1-organyl-2-lyso-sn-glycero-3-phosphocholine.

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