glycoprotein 6-alpha-L-fucosyltransferase EC#: 2.4.1.68; ChemWhat Code: 1377338

Product Name glycoprotein 6-alpha-L-fucosyltransferase
Example Structure Example Structure of glycoprotein 6-alpha-L-fucosyltransferase EC#: 2.4.1.68
Synonyms 6FucT, alpha(1,6)FT, alpha(1,6)fucosyltransferase, alpha-1,6-fucosyltransferase, alpha-6-fucosyltransferase, alpha1,6-fucosyltransferase, alpha1,6-FucT, alpha1,6FucT, alpha1-6,fucosyltransferase, alpha1-6FucT, alpha6FucT, fucosyltransferase 8, fucosyltransferase, guanosine diphosphofucose-glycoprotein, FUT8, GDP-fucose glycoprotein fucosyltransferase, GDP-fucose-glycoprotein fucosyltransferase, GDP-L-fuc:N-acetyl-beta-D-glucosaminide alpha1-6fucosyltransferase, GDP-L-fucose-glycoprotein fucosyltransferase, GDP-L-fucose:2-acetamido-2-deoxy-beta-D-glucoside 6-alpha-L-fucosyltransferase, GDPfucose glycoprotein fucosyltransferase, glycoprotein fucosyltransferase, guanosine diphosphofucose-glycoprotein fucosyltransferase, NodZ, NodZ fucosyltransferase
EC Number 2.4.1.68
CAS Registry Number 9033/8/3
Comments This enzyme catalyses a reaction similar to that of EC 2.4.1.214, glycoprotein 3¦Á-L-fucosyltransferase, but transfers the L-fucosyl group from GDP-¦Â-L-fucose to form an ¦Á1,6-linkage rather than an ¦Á1,3-linkage.
Cofactor
History
Reactions GDP-beta-L-fucose + N(4)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D- mannosyl-(1->3)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl- (1->6))-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N- acetyl-beta-D-glucosaminyl)asparagine = Gdp + N(4)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-beta-D-mannosyl-(1->4)-N- acetyl-beta-D-glucosaminyl-(1->4)-(alpha-L-fucosyl-(1->6))-N-acetyl-beta- D-glucosaminyl)asparagine.

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