glycoprotein endo-alpha-1,2-mannosidase EC#: 3.2.1.130; ChemWhat Code: 1380024
| Product Name | glycoprotein endo-alpha-1,2-mannosidase |
| Example Structure |  |
| Synonyms | alpha-1,2-endomannosidase, alpha-endomannosidase, BtGH99, endo-alpha-1,2-mannanase, endo-alpha-1,2-mannosidase, endo-alpha-1->2-mannanase, endo-alpha-D-mannosidase, endo-alpha-mannosidase, endomannosidase, GH99, glucosyl mannosidase, glucosylmannosidase, Golgi endo-a-mannosidase, Golgi-endomannosidase, MANEA |
| EC Number | 3.2.1.130 |
| CAS Registry Number | |
| Comments | The enzyme catalyses the hydrolysis of the terminal ¦Á-D-glucosyl-(1¡ú3)-D-mannosyl unit from the GlcMan9(GlcNAc)2?oligosaccharide component of?N-glucosylated proteins during their processing in the Golgi apparatus. The name for the isomer is based on a nomenclature proposed by Prien et al [7]. |
| Cofactor | |
| History | |
| Reactions | GlcMan(9)GlcNAc(2)-[protein] + H(2)O = Man(8)GlcNAc(2)-[protein] (isomer 8A(1,2,3)B(1,2)) + alpha-D-glucosyl-(1->3)-alpha-D-mannopyranose. |
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