O-mannose kinase, protein O-mannose kinase, SGK196
EC Number
2.7.1.183
CAS Registry Number
Comments
In humans this phosphorylated trisaccharide is attached to an?L-threonine residue of ¦Á-dystroglycan, an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains, and is important for its activity.
Cofactor
History
Reactions
Atp + O(3)-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D- glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl/L-seryl-[protein] = Adp + O(3)-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D- glucosaminyl-(1->4)-alpha-D-(6-phospho)mannosyl)-L-threonyl/L-seryl- [protein].
