Granzyme A EC#: 3.4.21.78; ChemWhat Code: 1380599
| Product Name | Granzyme A |
| Example Structure |  |
| Synonyms | Autocrine thymic lymphoma granzyme-like serine protease, CTL tryptase, CTLA3, Cytotoxic T lymphocyte serine protease, GrA, Gzm A, Gzma, GzmA/K, H factor, Hanukkah factor, HuTPS, T-cell associated protease 1, T-cell derived serine proteinase 1, TSP-1 |
| EC Number | 3.4.21.78 |
| CAS Registry Number | 143180-73-8 |
| Comments | From cytotoxic T lymphocyte granules. In peptidase family?S1?(trypsin family). The human enzyme does not cleave Phe©à-. |
| Cofactor | |
| History | |
| Reactions | Hydrolysis of proteins, including fibronectin, type Iv collagen and nucleolin. Preferential cleavage: -Arg-|-Xaa-, -Lys-|-Xaa- >> -Phe-|-Xaa- in small molecule substrates |
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