grixazone synthase EC#: 1.10.3.15; ChemWhat Code: 1374803
| Product Name | grixazone synthase |
| Example Structure |  |
| Synonyms | GriF |
| EC Number | 1.10.3.15 |
| CAS Registry Number | |
| Comments | A type 3 multi copper protein. The enzyme, isolated from the bacterium Streptomyces griseus, catalyses an 8 electron oxidation. Activation of the enzyme requires a copper chaperone (GriE). It also acts on 3-amino-4-hydroxybenzaldehyde, giving grixazone A. The second aldehyde group is presumably lost as formate. The enzyme also catalyses the reaction of EC 1.10.3.4 O-aminophenol oxidase. |
| Cofactor | Cu cation |
| History | |
| Reactions | 2 3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + 2 O(2) = grixazone B + 4 H(2)O + CO(2). |
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