GTP cyclohydrolase II EC#: 3.5.4.25; ChemWhat Code: 1381463
| Product Name | GTP cyclohydrolase II |
| Example Structure |  |
| Synonyms | 3,4-dihydroxy-2-butanone 4-phosphate synthase, GCH II, GCH II/III, GCH-II, GCHII, GTP cyclohydrolase II, GTP cyclohydrolase-II, GTP-8-formylhydrolase, GTPCH II, GTPCH-II, guanosine triphosphate cyclohydrolase II, guanosine triphosphate cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase, guanosine-5′-triphosphate cyclohydrolase-II, More, NbRibA, RibA, ribA2, RIBIV |
| EC Number | 3.5.4.25 |
| CAS Registry Number | |
| Comments | Two C-N bonds are hydrolysed, releasing formate, with simultaneous removal of the terminal diphosphate. |
| Cofactor | |
| History | |
| Reactions | Gtp + 3 H(2)O = formate + 2,5-diamino-6-hydroxy-4-(5-phospho-D- ribosylamino)pyrimidine + diphosphate. |
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