heme o synthase EC#: 2.5.1.141; ChemWhat Code: 1378086
Product Name
heme o synthase
Example Structure
Synonyms
caaE, Cox10, coxD, CtaB, cyoE, CyoE protein, heme A:farnesyltransferase, heme B farnesyltransferase, heme o synthase, HOS, JW0418, protoheme IX farnesyltransferase
EC Number
2.5.1.141
CAS Registry Number
Comments
The enzyme, found in many archaea, bacteria, and eukaryotes, produces heme o, which in many cases is further modified into heme a. In organisms that produce heme a, the enzyme forms a complex with heme a synthase. In some archaeal species the enzyme transfers a geranylgeranyl group instead of a farnesyl group.
Cofactor
History
Reactions
(2E,6E)-farnesyl diphosphate + protoheme Ix = diphosphate + ferroheme o.
