| Product Name |
heme oxygenase (biliverdin-IX-beta and delta-forming) |
| Example Structure |
 |
| Synonyms |
biliverdin IXbeta/delta-selective heme oxygenase, BphO, heme-PigA heme oxygenase, heme-PigA(HO), HemO, PigA |
| EC Number |
1.14.99.58 |
| CAS Registry Number |
|
| Comments |
The enzyme, characterized from the bacterium Pseudomonas aeruginosa, differs from EC 1.14.15.20, heme oxygenase (biliverdin-producing, ferredoxin), in that the heme substrate is rotated by approximately 110 degrees within the active site, resulting in cleavage at a different part of the ring. It forms a mixture of about 70% biliverdin-IX-¦Ä and 30% biliverdin-IX-¦Â. |
| Cofactor |
|
| History |
|
| Reactions |
(1) Protoheme + 3 reduced acceptor + 3 O(2) = biliverdin-IX-delta + Co + Fe(2+) + 3 acceptor + 3 H(2)O. (2) Protoheme + 3 reduced acceptor + 3 O(2) = biliverdin-IX-beta + Co + Fe(2+) + 3 acceptor + 3 H(2)O. |
