| Synonyms |
cone transducin, EC 3.6.1.46, EF-2, EF-G, elongation factor 2, G alpha i2, G alpha q, G alpha11, G alphaQ, G betagamma, G12, G13, Galpha protein, Galpha-subunit, Galpha16, Galphai1, Galphai3, Galphao, GI, GmGalpha protein, GPA1, Gq, Gs alpha, GTP phosphohydrolase, GTPase, guanosine 5′-triphosphatase, guanosine triphosphatase, heterotrimeric G protein, heterotrimeric G protein alpha subunit, heterotrimeric G protein family, heterotrimeric G protein Gsalpha, heterotrimeric G-protein, heterotrimeric G-protein GTPase, heterotrimeric GTPase, phosphatase, guanosine tri-, photoreceptor-specific G protein, Rab1, Rab1 GTPase, Rab1a, ribosomal GTPase, SsEF-2, transducin, transducin GTPase |
| Comments |
This group comprises GTP-hydrolysing systems, where GTP and GDP alternate in binding. This group includes stimulatory and inhibitory G-proteins such as Gs, Gi, Go?and Golf, targetting adenylate cyclase and/or K+?and Ca2+?channels; Gq?stimulating phospholipase C; transducin activating cGMP phosphodiesterase; gustducin activating cAMP phosphodiesterase. Golf?is instrumental in odour perception, transducin in vision and gustducin in taste recognition. At least 16 different ¦Á subunits (39-52 kDa), 5 ¦Â subunits (36 kDa) and 12 ¦Ã subunits (6-9 kDa) are known. |
