HIV-1 retropepsin EC#: 3.4.23.16; ChemWhat Code: 1380866
| Product Name | HIV-1 retropepsin |
| Example Structure |  |
| Synonyms | CRF01_AE protease, Gag protease, HIV aspartyl protease, HIV PR, HIV-1 aspartyl protease, HIV-1 PR, HIV-1 protease, HIV-1 proteinase, HIV-1PR, HIVPR, human immunodeficiency virus 1 retropepsin, human immunodeficiency virus type 1 protease, human immunodeficiency virus type I protease, More, PR, PR1, retropepsin, retroproteinase |
| EC Number | 3.4.23.16 |
| CAS Registry Number | 144114-21-6 |
| Comments | Present in human immunodeficiency virus type 1. Contributes to the maturation of the viral particle, and is a target of antiviral drugs. Active enzyme is a dimer of identical 11-kDa subunits. Similar enzymes occur in other retroviruses [1]. Type example of peptidase family?A2. |
| Cofactor | |
| History | |
| Reactions | Specific for a P1 residue that is hydrophobic, and P1′ variable, but often Pro. |
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