homocitrate synthase EC#: 2.3.3.14; ChemWhat Code: 1377214
| Product Name | homocitrate synthase |
| Example Structure |  |
| Synonyms | 2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating), acetyl-coenzyme A: 2-ketoglutarate C-transferase, acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase, EC 4.1.3.21, HCS, HcsA, homocitrate synthase, homocitrate synthetase, homocitrate-condensing enzyme, homocondensing enzyme, LYS20, LYS21, Lys21p, LYS22, Lys22p, nifV2, SpHCS, synthase, homocitrate, TtHCS |
| EC Number | 2.3.3.14 |
| CAS Registry Number | 9075-60-9 |
| Comments | Belongs in the ¦Á-aminoadipate pathway of lysine synthesis, along with EC 4.2.1.36, homoaconitate hydratase. The enzyme also acts with oxaloacetate as substrate, but more slowly [2,3]. |
| Cofactor | |
| History | |
| Reactions | Acetyl-CoA + H(2)O + 2-oxoglutarate = (R)-2-hydroxybutane-1,2,4- tricarboxylate + CoA. |
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