horrilysin EC#: 3.4.24.47; ChemWhat Code: 1381037

Product Name horrilysin
Example Structure Example Structure of horrilysin EC#: 3.4.24.47
Synonyms Crotalus horridus metalloendopeptidase, Hemorrhagic proteinase IV, HP-IV, Proteinase, Crotalus horridus horridus venom hemorrhagic
EC Number 3.4.24.47
CAS Registry Number 84056-81-5
Comments A 56 kDa hemorrhagic endopeptidase from the venom of the timber rattlesnake (Crotalus horridus horridus) that cleaves basement membrane, hide powder and fibrinogen.
Cofactor Zn2+
History
Reactions Cleavage of only the single bond 14-Ala-|-Leu-15 in the insulin B chain, 12-Ser-|-Leu-13 in the A chain, and Ile-|-Gly, Pro-|-Ala, and Ser-|-Trp in mellitin.

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