HslU-HslV peptidase EC#: 3.4.25.2; ChemWhat Code: 1381108

Product Name HslU-HslV peptidase
Example Structure Example Structure of HslU-HslV peptidase EC#: 3.4.25.2
Synonyms AAA+ HslUV protease, AAA+ protease HslUV, ATP-dependent protease, ATP-dependent protease hslV, ClpQ, ClpQY, ClpYQ, ClpYQ complex, ClpYQ protease, CodW, CodW-CodX, heat shock protein hslV, HslU ATPase, HslU chaperone, HslU/HslV, HslUV, HslUV complex, HslUV protease, HslUV protease-chaperone complex, HslV, HslV peptidase, HslV protease, HslV-HslU, hslVU, HslVU ATP-dependent protease, HslVU protease, PfHslUV, T01.006
EC Number 3.4.25.2
CAS Registry Number
Comments The HslU subunit of the HslU¡ªHslV complex functions as an ATP dependent ‘unfoldase’. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolysed by HslV [5]. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis [7]. In peptidase family?T1.
Cofactor
History
Reactions ATP-dependent cleavage of peptide bonds with broad specificity.

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