hydrogenase [ambiguous], NADP-dependent hydrogenase, NADP-linked hydrogenase, NADP-reducing hydrogenase, NADPH-dependent hydrogenase I, NiFe-hydrogenase, SHI, soluble hydrogenase I, [NiFe]-hydrogenase
EC Number
1.12.1.3
CAS Registry Number
9027/5/8
Comments
The protein from the bacterium Desulfovibrio fructosovorans is an iron-sulfur protein that exclusively functions as a hydrogen dehydrogenase, while the enzyme from the archaeon Pyrococcus furiosus is a nickel, iron, iron-sulfur protein, that is part of a heterotetrameric complex where the ¦Á and ¦Ä subunits function as a hydrogenase while the ¦Â and ¦Ã subunits function as sulfur reductase (EC 1.12.98.4, sulfhydrogenase). Different from EC 1.12.1.5, hydrogen dehydrogenase [NAD(P)+].
