hydrogenase (NAD+, ferredoxin) EC#: 1.12.1.4; ChemWhat Code: 1374870
| Product Name | hydrogenase (NAD+, ferredoxin) |
| Example Structure | ![]() |
| Synonyms | bifurcating [FeFe] hydrogenase, electron-bifurcating ferredoxin- and NAD-dependent hydrogenase, Fe-only hydrogenase, HydABC, HydC, HydF, iron hydrogenase, NAD(P)+-linked [FeFe]-hydrogenase, [FeFe]-hydrogenase, [FeFe]-type hydrogenase |
| EC Number | 1.12.1.4 |
| CAS Registry Number | |
| Comments | The enzyme from Thermotoga maritima contains a [FeFe] cluster (H-cluster) and iron-sulfur clusters. It works in the direction evolving hydrogen as a means of eliminating excess reducing equivalents. |
| Cofactor | |
| History | |
| Reactions | 2 H(2) + NAD(+) + 2 oxidized ferredoxin = 5 H(+) + Nadh + 2 reduced ferredoxin. |
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