| Product Name |
hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) |
| Example Structure |
 |
| Synonyms |
CbiA, cobalamin biosynthesis aminotransferase, CobB, cobyric acid synthase, cobyrinic acid a,c-diamide synthase, new NaMN:Me2Bza phosphoribosyltransferase enzyme |
| EC Number |
6.3.5.9 |
| CAS Registry Number |
132053-22-6 |
| Comments |
This step in the aerobic biosynthesis of cobalamin generates hydrogenobyrinic acid?a,c-diamide, the substrate required by EC?6.6.1.2, cobaltochelatase, which adds cobalt to the macrocycle. |
| Cofactor |
|
| History |
|
| Reactions |
2 Atp + hydrogenobyrinic acid + 2 L-glutamine + 2 H(2)O = 2 adp + 2 phosphate + hydrogenobyrinic acid a,c-diamide + 2 L-glutamate. |
