hydroxyacid-oxoacid transhydrogenase EC#: 1.1.99.24; ChemWhat Code: 1373698
| Product Name | hydroxyacid-oxoacid transhydrogenase |
| Example Structure |  |
| Synonyms | HOT, hydroxyacid-oxoacid transhydrogenase, iron-dependent alcohol dehydrogenase ADHFe1, transhydrogenase, hydroxy acid-oxo acid |
| EC Number | 1.1.99.24 |
| CAS Registry Number | 117698-31-4 |
| Comments | 4-Hydroxybutanoate and (R)-2-hydroxyglutarate can also act as donors; 4-oxobutanoate can also act as acceptor. |
| Cofactor | |
| History | |
| Reactions | (1) (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2- hydroxyglutarate. (2) 4-hydroxybutanoate + 2-oxoglutarate = succinic semialdehyde + (R)-2- hydroxyglutarate. |
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