| Product Name |
hydroxyacid-oxoacid transhydrogenase |
| Example Structure |
 |
| Synonyms |
HOT, hydroxyacid-oxoacid transhydrogenase, iron-dependent alcohol dehydrogenase ADHFe1, transhydrogenase, hydroxy acid-oxo acid |
| EC Number |
1.1.99.24 |
| CAS Registry Number |
117698-31-4 |
| Comments |
4-Hydroxybutanoate and (R)-2-hydroxyglutarate can also act as donors; 4-oxobutanoate can also act as acceptor. |
| Cofactor |
|
| History |
|
| Reactions |
(1) (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2- hydroxyglutarate. (2) 4-hydroxybutanoate + 2-oxoglutarate = succinic semialdehyde + (R)-2- hydroxyglutarate. |
