hygromycin B 4-O-kinase EC#: 2.7.1.163; ChemWhat Code: 1378547
| Product Name | hygromycin B 4-O-kinase |
| Example Structure |  |
| Synonyms | Hm phosphotransferase, HPH, Hph5, HPT, hptII, hygromycin B phosphotransferase, hygromycin B4-O-phosphohygromycin, hygromycin phosphotransferase, hygromycin-B kinase, hygromycin-phosphotransferase, HyR |
| EC Number | 2.7.1.163 |
| CAS Registry Number | |
| Comments | Phosphorylates the antibiotic hygromycin B. Whereas the enzyme from?Streptomyces hygroscopicus?(EC?2.7.1.119; hygromycin-B 7”-O-kinase) catalyses the formation of 7”-O-phosphohygromycin B, this enzyme, found in?Escherichia coli?carrying a plasmid conferring resistance to hygromycin-B, forms 4-O-phosphohygromycin B. |
| Cofactor | |
| History | |
| Reactions | Atp + hygromycin b = adp + 4-O-phosphohygromycin b. |
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