IgA-specific metalloendopeptidase EC#: 3.4.24.13; ChemWhat Code: 1380959
| Product Name | IgA-specific metalloendopeptidase |
| Example Structure |  |
| Synonyms | HP1022, Iga, IgA protease, IgA1 protease, IgA1 proteinase, IgA1-specific proteinase, IgA1P, igaB, IgaB2, immunoglobulin A1 protease, proteinase, immunoglobulin A1 |
| EC Number | 3.4.24.13 |
| CAS Registry Number | 72231-73-3 |
| Comments | A 190 kDa enzyme found in several pathogenic species of?Streptococcus?such as?sanguis?and?pneumoniae. Type example of peptidase family?M26. There is also an IgA-specific prolyl endopeptidase of serine-type (see EC?3.4.21.72, IgA-specific serine endopeptidase). |
| Cofactor | Zn2+ |
| History | |
| Reactions | Cleavage of Pro-|-Thr bond in the hinge region of the heavy chain of human IgA. |
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