IgA-specific serine endopeptidase EC#: 3.4.21.72; ChemWhat Code: 1380587
| Product Name | IgA-specific serine endopeptidase |
| Example Structure |  |
| Synonyms | Iga, IgA protease, IgA proteinase, IgA-specific proteinase, IgA1 protease, IgA1-specific protease, IgaA1, IgaA2, IgAP, Immunoglobulin A protease, Immunoglobulin A proteinase, immunoglobulin A1 protease, NMB IgA1 protease, Proteinase, immunoglobulin A, serine-type IgA1 protease, serine-type immunoglobulin A1 protease, type 2 IgA1 protease |
| EC Number | 3.4.21.72 |
| CAS Registry Number | 55127-02-1 |
| Comments | Species variants differing slightly in specificity are secreted by Gram-negative bacteria?Neisseria gonorrhoeae?and?Haemophilus influenzae. Type example of peptidase family?S6. Some other bacterial endopeptidases with similar specificity are of metallo- type (see EC?3.4.24.13, IgA-specific metalloendopeptidase). |
| Cofactor | |
| History | |
| Reactions | Cleavage of immunoglobulin A molecules at certain Pro-|-Xaa bonds in the hinge region. No small molecule substrates are known. |
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