infectious pancreatic necrosis birnavirus Vp4 peptidase EC#: 3.4.21.115; ChemWhat Code: 1380663

Product Name infectious pancreatic necrosis birnavirus Vp4 peptidase
Example Structure Example Structure of infectious pancreatic necrosis birnavirus Vp4 peptidase EC#: 3.4.21.115
Synonyms avian infectious busrsal disease birnavirus Vp4 endopeptidase, blotched snakehead birnavirus endopeptidase, Drosophila X virus Vp4 protease, equine arterivirus serine peptidase, infectious pancreatic necrosis birnavirus Vp4 protease, NS, NS protease, S50.001, VP4
EC Number 3.4.21.115
CAS Registry Number
Comments Infectious pancreatic necrosis virus (IPNV) is a birnavirus that causes an acute, contagious disease in young salmonid fish [2]. As with most viruses that infect eukaryotic cells, the proteolytic processing of viral precursor proteins is a crucial step in the life cycle of this virus [2]. pVP2 is converted into VP2 by cleavage near the carboxy end of pVP2. This cleavage is most likely due to host-cell proteases rather than VP4 [2,3]. Differs from most serine peptidases in not having the catalytic triad Ser-His-Asp [2]. Belongs in peptidase family?S50.
Cofactor
History
Reactions Cleaves the (Ser/Thr)-Xaa-Ala-|-(Ser/Ala)-Gly motif in the polyprotein NH(2)-pVP2-VP4-VP3-Cooh of infectious pancreatic necrosis virus at the pVP2-VP4 and VP4-VP3 junctions.

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