inositol-polyphosphate multikinase EC#: 2.7.1.151; ChemWhat Code: 1378526

Product Name inositol-polyphosphate multikinase
Example Structure Example Structure of inositol-polyphosphate multikinase EC#: 2.7.1.151
Synonyms 1,3,4,6-tetrakisphosphate 5-kinase, 5-kinase, Arg82, ArgRIII, ARGSIII, AtIpk2a, AtIpk2b, AtIpk2beta, Impk, inositol 1,4,5-trisphosphate 3-kinase, inositol phosphate multikinase, inositol phosphate multikinase 2, inositol polyphosphate 6-/3-kinase, inositol polyphosphate kinase, inositol polyphosphate multikinase, Ins(1,4,5)P3 3-kinase, InsP4 5-kinase, IP3 3-kinase, IP3/IP4 6-/3-kinase, IP3K, IPK, Ipk2, Ipk2/Impk/IP3K, Ipk2a, Ipk2beta/IP3K, IPKII, IPMK, ITPK1, Kcs1, Kcs1p, More, phosphoinositol kinase, PI3K, StIPMK
EC Number 2.7.1.151
CAS Registry Number
Comments This enzyme also phosphorylates Ins(1,4,5)P3?to Ins(1,3,4,5)P4, Ins(1,3,4,5)P4?to Ins(1,3,4,5,6)P5, and Ins(1,3,4,5,6)P4?to Ins(PP)P4, isomer unknown. The enzyme from the plant?Arabidopsis thaliana?can also phosphorylate Ins(1,3,4,6)P4?and Ins(1,2,3,4,6)P5?at the?D-5-position to produce 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate (InsP6), respectively [3]. Yeast produces InsP6?from Ins(1,4,5)P3?by the actions of this enzyme and EC?2.7.1.158, inositol-pentakisphosphate 2-kinase [4].
Cofactor
History
Reactions 2 Atp + 1D-myo-inositol 1,4,5-trisphosphate = 2 adp + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.

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