iridoid synthase EC#: 1.3.1.99; ChemWhat Code: 1374070
| Product Name | iridoid synthase |
| Example Structure |  |
| Synonyms | 1,4-Reductase, 10-hydroxygeraniol oxidoreductase, Cr10HGO, CrIS, CrISY, CrP5betaR4, CrP5betaR5, iridoid cyclase, IRIS, ISY, nepetalactol synthase, OeISY, P5betaR5 |
| EC Number | 1.3.1.99 |
| CAS Registry Number | |
| Comments | Isolated from the plant Catharanthus roseus. The reaction may involve cyclization via a Diels-Alder or Michael reaction. Iridoids are involved in the biosynthesis of many indole alkaloids. The cyclic hemiacetal is readily hydrolysed to the corresponding dial. |
| Cofactor | |
| History | |
| Reactions | (6E)-8-oxogeranial + NAD(P)H = cis-trans-nepetalactol + NAD(P)(+). |
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