isobutylamine N-monooxygenase EC#: 1.14.14.30; ChemWhat Code: 1375537

Product Name isobutylamine N-monooxygenase
Example Structure Example Structure of isobutylamine N-monooxygenase EC#: 1.14.14.30
Synonyms IBAH, isobutylamine N-hydroxylase, vlmH
EC Number 1.14.14.30
CAS Registry Number
Comments The enzyme, characterized from the bacterium Streptomyces viridifaciens, is part of a two component system that also includes a flavin reductase, which provides reduced flavin mononucleotide for this enzyme. The enzyme, which is involved in the biosynthesis of the azoxy antibiotic valanimycin, has a similar activity with either FMNH2 or FADH2. It exhibits broad specificity, and also accepts propan-1-amine, butan-1-amine, butan-2-amine and benzylamine.
Cofactor
History
Reactions (1) 2-methylpropan-1-amine + FADH(2) + O(2) = N-(2-methylpropyl)hydroxylamine + Fad + H(2)O. (2) 2-methylpropan-1-amine + FMNH(2) + O(2) = N-(2-methylpropyl)hydroxylamine + Fmn + H(2)O.

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