isobutylamine N-monooxygenase EC#: 1.14.14.30; ChemWhat Code: 1375537
| Product Name | isobutylamine N-monooxygenase |
| Example Structure |  |
| Synonyms | IBAH, isobutylamine N-hydroxylase, vlmH |
| EC Number | 1.14.14.30 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the bacterium Streptomyces viridifaciens, is part of a two component system that also includes a flavin reductase, which provides reduced flavin mononucleotide for this enzyme. The enzyme, which is involved in the biosynthesis of the azoxy antibiotic valanimycin, has a similar activity with either FMNH2 or FADH2. It exhibits broad specificity, and also accepts propan-1-amine, butan-1-amine, butan-2-amine and benzylamine. |
| Cofactor | |
| History | |
| Reactions | (1) 2-methylpropan-1-amine + FADH(2) + O(2) = N-(2-methylpropyl)hydroxylamine + Fad + H(2)O. (2) 2-methylpropan-1-amine + FMNH(2) + O(2) = N-(2-methylpropyl)hydroxylamine + Fmn + H(2)O. |
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