isoflavone 4′-O-methyltransferase EC#: 2.1.1.46; ChemWhat Code: 1376196
| Product Name | isoflavone 4′-O-methyltransferase | 
| Example Structure | ![]()  | 
| Synonyms | S-adenosylmethionine:isoflavone 4′-O-methyltransferase | 
| EC Number | 2.1.1.46 | 
| CAS Registry Number | 55071-80-2 | 
| Comments | Requires Mg2+ for activity. The enzyme catalyses the methylation of daidzein and genistein. It does not methylate naringenin, apigenin, luteolin or kaempferol. | 
| Cofactor | Mg2+ | 
| History | |
| Reactions | S-adenosyl-L-methionine + a 4′-hydroxyisoflavone = S-adenosyl-L- homocysteine + a 4′-methoxyisoflavone. | 
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