A cytochrome P450 (heme thiolate) enzyme found in plants. The enzyme acts on jasmonoyl-L-amino conjugates, catalysing the hydroxylation of the C-12 position of the jasmonic acid chain. While the best studied substrate is (+)-7-epi-jasmonoyl-L-isoleucine, the enzyme was shown to be active with jasmonoyl-L-valine and jasmonoyl-L-phenylalanine, and is likely to be active with other jasmonoyl-amino acid conjugates.
Cofactor
heme-thiolate
History
Reactions
A jasmonoyl-L-amino acid + [reduced NADPH–hemoprotein reductase] + O(2) = a 12-hydroxyjasmonoyl-L-amino acid + [oxidized NADPH–hemoprotein reductase] + H(2)O.
