(KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase EC#: 2.4.99.13; ChemWhat Code: 1377856
| Product Name | (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase |
| Example Structure |  |
| Synonyms | 3-deoxy-D-manno-2-octulosonic acid transferase, 3-deoxy-D-manno-oct-2-ulosonic acid transferase, 3-deoxy-D-manno-oct-2-ulosonic acid transferases, 3-deoxy-D-manno-octulosonic acid transferase, 3-deoxy-manno-octulosonic acid transferase, Kdo transferase, KdtA, multi-functional Kdo-transferase |
| EC Number | 2.4.99.13 |
| CAS Registry Number | |
| Comments | The bifunctional enzyme from Escherichia coli transfers two 3-deoxy-D-manno-octulosonate residues to lipid IVA (cf. EC 2.4.99.12 [lipid IVA 3-deoxy-D-manno-octulosonic acid transferase]) [1]. The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-octulosonate residues and generate genus-specific epitopes [4]. |
| Cofactor | |
| History | |
| Reactions | Alpha-Kdo-(2->6)-lipid IV(A) + CMP-beta-Kdo = alpha-Kdo-(2->4)-alpha- Kdo-(2->6)-lipid IV(A) + Cmp. |
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