L-2-hydroxycarboxylate dehydrogenase (NAD+) EC#: 1.1.1.337; ChemWhat Code: 1373453
| Product Name | L-2-hydroxycarboxylate dehydrogenase (NAD+) |
| Example Structure |  |
| Synonyms | |
| EC Number | 1.1.1.337 |
| CAS Registry Number | |
| Comments | The enzyme from the archaeon Methanocaldococcus jannaschii acts on multiple L-2-hydroxycarboxylates including (2R)-3-sulfolactate, (S)-malate, (S)-lactate, and (S)-2-hydroxyglutarate [3]. Note that (2R)-3-sulfolactate has the same stereo configuration as (2S)-2-hydroxycarboxylates. |
| Cofactor | |
| History | |
| Reactions | A (2S)-2-hydroxycarboxylate + NAD(+) = a 2-oxocarboxylate + nadh. |
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