L-asparagine hydroxylase EC#: 1.14.11.39; ChemWhat Code: 1375128

Product Name L-asparagine hydroxylase
Example Structure Example Structure of L-asparagine hydroxylase EC#: 1.14.11.39
Synonyms AsnO, asparagine oxygenase, L-asparagine 3-hydroxylase, SCO3236
EC Number 1.14.11.39
CAS Registry Number
Comments Requires Fe2+. The enzyme is only able to hydroxylate free L-asparagine. It is not active toward D-asparagine. The ¦Â-hydroxylated asparagine produced is incorporated at position 9 of the calcium-dependent antibiotic (CDA), an 11-residue non-ribosomally synthesized acidic lipopeptide lactone.
Cofactor Fe2+
History
Reactions L-asparagine + 2-oxoglutarate + O(2) = (2S,3S)-3-hydroxyasparagine + succinate + CO(2).

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