L-cysteine desulfidase EC#: 4.4.1.28; ChemWhat Code: 1382946
| Product Name | L-cysteine desulfidase |
| Example Structure |  |
| Synonyms | aecD, At5g28030, CDL, CFL1_01513, cystalysin, DES1, L-cysteine desulfhydrase, les, MJ1025 |
| EC Number | 4.4.1.28 |
| CAS Registry Number | |
| Comments | The enzyme from the archaeon?Methanocaldococcus jannaschii?contains a [4Fe-4S] cluster and is specific for?L-cysteine (cf. EC?4.4.1.1, cystathionine ¦Ã-lyase). It cleaves a carbon-sulfur bond releasing sulfide and the unstable enamine product 2-aminoprop-2-enoate that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia. The same reaction can also be catalysed by some pyridoxal-phosphate proteins (cf. EC?4.4.1.1, cystathionine ¦Ã-lyase). |
| Cofactor | |
| History | |
| Reactions | L-cysteine + H(2)O = sulfide + NH(3) + pyruvate. |
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