L-isoleucine 4-hydroxylase EC#: 1.14.11.45; ChemWhat Code: 1375137
| Product Name | L-isoleucine 4-hydroxylase |
| Example Structure |  |
| Synonyms | HilB, IDO, isoleucine 4-hydroxylase, L-4′-hydroxyisoleucine, 2-oxoglutarate: oxygen oxidoreductase (4-hydroxylating), L-isoleucine dioxygenase, L-isoleucine-4′-dioxygenase |
| EC Number | 1.14.11.45 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the bacterium Bacillus thuringiensis, can also catalyse the hydroxylation of L-leucine, L-norvaline, L-norleucine, and L-allo-isoleucine, as well as the sulfoxidation of L-methionine, L-ethionine, S-methyl-L-cysteine, S-ethyl-L-cysteine, and S-allyl-L-cysteine. |
| Cofactor | |
| History | |
| Reactions | L-isoleucine + 2-oxoglutarate + O(2) = (4S)-4-hydroxy-L-isoleucine + succinate + CO(2). |
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