L-ornithine N5-monooxygenase (NADPH) EC#: 1.14.13.195; ChemWhat Code: 1375434

Product Name L-ornithine N5-monooxygenase (NADPH)
Example Structure Example Structure of L-ornithine N5-monooxygenase (NADPH) EC#: 1.14.13.195
Synonyms Af-OMO, CchB, flavin-dependent monooxygenase, L-Orn N5-oxygenase, L-ornithine N5-hydroxylase, L-ornithine-Ndelta-oxygenase, monooxygenase EtcB, omega-amino acid monooxygenase, ornithine hydroxylase, ornithine N5-monooxygenase, PsbA, PvdA, SidA, siderophore A
EC Number 1.14.13.195
CAS Registry Number
Comments A flavoprotein (FAD). The enzyme is involved in biosynthesis of N5-hydroxy-L-ornithine, N5-formyl-N5-hydroxy-L-ornithine or N5-acetyl-N5-hydroxy-L-ornithine. These nonproteinogenic amino acids are building blocks of siderophores produced by some bacteria (e.g. Streptomyces coelicolor, Saccharopolyspora erythraea and Pseudomonas aeruginosa). The enzyme is specific for NADPH. cf. EC 1.14.13.196, L-ornithine N5-monooxygenase [NAD(P)H].
Cofactor FAD
History
Reactions L-ornithine + Nadph + O(2) = N(5)-hydroxy-L-ornithine + NADP(+) + H(2)O.

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