Lactocepin EC#: 3.4.21.96; ChemWhat Code: 1380630
| Product Name | Lactocepin |
| Example Structure |  |
| Synonyms | cell envelope associated proteinase, cell envelope proteinase, cell wall anchored proteinase, Cell wall-associated serine proteinase, cell-bound cell envelope proteinase, Cell-envelope proteinase, Cell-envelope-located serine proteinase, Cell-wall-bound proteinase, CEP, Extracellular lactococcal proteinase, Lactocepin, Lactocepin I, lactococcal cell envelope proteinase, Lactococcal cell envelope-associated proteinase, Lactococcal cell wall-associated proteinase, Lactococcal PI-type proteinase, Lactococcal PIII-type poteinase, Lactococcal proteinase, Lactococcal proteinase PI, LP151, PrtH, PrtH2, PrtP, PrtP proteinase |
| EC Number | 3.4.21.96 |
| CAS Registry Number | 205510-58-3 |
| Comments | Associated with the cell envelope of?Lactococcus lactis?and attached via a C-terminal membrane anchor sequence. Responsible for the hydrolysis of casein in milk and the provision of peptides essential to cell growth. Important in cheese making and the production of lactic casein, being required for rapid growth to high cell densities with concomitant production of adequate levels of lactic acid. Specificity differences between lactocepins from different starter strains may be partly responsible for imparting different flavour qualities to cheese [4]. In peptidase family?S8?(subtilisin family). |
| Cofactor | |
| History | |
| Reactions | Endopeptidase activity with very broad specificity, although some subsite preference have been noted, e.g. large hydrophobic residues in the P1 and P4 positions, and Pro in the P2 position. Best known for its action on caseins, although it has been shown to hydrolyze hemoglobin and oxidized insulin B-chain. |
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