Legumain EC#: 3.4.22.34; ChemWhat Code: 1380737

Product Name Legumain
Example Structure Example Structure of Legumain EC#: 3.4.22.34
Synonyms AEP, Antigen Sj32, Antigen SM32, As-specific vacuolar cysteine proteinase, Asn-specific vacuolar cysteine proteinase, asparagine endopeptidase, asparaginly endopeptidase, asparaginyl endopepidase, Asparaginyl endopeptidase, asparaginyl endopeptidase legumain, asparaginyl endopeptidase,, asparaginyl proteinase, asparaginyl-specific cysteine endopeptidase, asparagyl-endopeptidase, aspartate-specific endopeptidase, Bean endopeptidase, C197 legumain, c197 Sm32, cysteine protease 1, hemoglobinase, HlLgm, HlLgm2, IrAE, IrAE protein, LeG, Leg-2, Leg-4, Leg1, Leg2, Leg3, Leg4, Leg5, legumain, LGMN, lysosomal asparaginycysteine endopeptidase, lysosomal asparaginyl endopeptidase, lysosomal cysteine proteinase, More, N197 legumain, osteoclast inhibitory peptide 2, Ov-aep-1, Phaseolin, Proteinase B, PrVPE1, schistosome legumain, Sj32, Sm32, SmAE, SmAE protein, SPAE, TvAE1, vacuolar processing enzyme, vacuolar processing enzyme 1a, vacuolar processing enzyme 1b, vacuolar processing enzyme 2, vacuolar processing enzyme 3, Vicilin peptidohydrolase, VPE, VPE1a, VPE1b, VPE2, VPE3
EC Number 3.4.22.34
CAS Registry Number 149371-18-6
Comments Best known from legume seeds, the trematode?Schistosoma mansoni?and mammalian lysosomes. Not inhibited by compound E-64. Type example of peptidase family?C13.
Cofactor
History
Reactions Hydrolysis of proteins and small molecule substrates at -Asn-|-Xaa- bonds.

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