levopimaradiene synthase EC#: 4.2.3.32; ChemWhat Code: 1382599

Product Name levopimaradiene synthase
Example Structure Example Structure of levopimaradiene synthase EC#: 4.2.3.32
Synonyms abietadiene synthase, levopimaradiene/abietadiene synthase, LP synthase, LPS, More, PaLAS, TPS-LAS
EC Number 4.2.3.32
CAS Registry Number
Comments In?Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides, a structurally unique family of diterpenoids that are highly specific platelet-activating-factor receptor antagonists [1]. Levopimaradiene is widely distributed in higher plants. In some species the enzyme also forms abietadiene, palustradiene, and neoabietadiene [2].
Cofactor
History
Reactions (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate.

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