| Product Name |
lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase |
| Example Structure |
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| Synonyms |
4-amino-4-deoxy-L-arabinose transferase, aminoarabinose transferase, arnT, L-Ara4N transferase |
| EC Number |
2.4.2.43 |
| CAS Registry Number |
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| Comments |
Integral membrane protein present in the inner membrane of certain Gram negative endobacteria. In strains that do not produce 3-deoxy-D-manno-octulosonic acid (Kdo), the enzyme adds a single arabinose unit to the 1-phosphate moiety of the tetra-acylated lipid A precursor, lipid IVA. In the presence of a Kdo disaccharide, the enzyme primarily adds an arabinose unit to the 4-phosphate of lipid A molecules. The Salmonella typhimurium enzyme can add arabinose units to both positions. |
| Cofactor |
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| History |
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| Reactions |
4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate. |
