lipid IVA palmitoyltransferase EC#: 2.3.1.251; ChemWhat Code: 1377082

Product Name lipid IVA palmitoyltransferase
Example Structure Example Structure of lipid IVA palmitoyltransferase EC#: 2.3.1.251
Synonyms crcA, lipid A palmitoyltransferase, PA1343, PagP
EC Number 2.3.1.251
CAS Registry Number
Comments Isolated from the bacteria Escherichia coli and Salmonella typhimurium. The enzyme prefers phosphatidylcholine with a palmitoyl group at the sn-1 position and palmitoyl or stearoyl groups at the sn-2 position. There is some activity with corresponding phosphatidylserines but only weak activity with other diacylphosphatidyl compounds. The enzyme also acts on Kdo-(2¡ú4)-Kdo-(2¡ú6)-lipid IVA.
Cofactor
History
Reactions (1) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A = 2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A. (2) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid II(A) = 2-acyl-sn-glycero-3-phosphocholine + lipid II(B). (3) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IV(A) = 2-acyl-sn-glycero-3-phosphocholine + lipid IV(B).

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