long-chain-3-hydroxyacyl-CoA dehydrogenase EC#: 1.1.1.211; ChemWhat Code: 1373288
| Product Name | long-chain-3-hydroxyacyl-CoA dehydrogenase |
| Example Structure |  |
| Synonyms | 2-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-oxoacyl-CoA thiolase, 3-hydroxyacyl-CoA dehydrogenase, beta-hydroxyacyl-CoA dehydrogenase, enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein, HADHA, LCHAD, LHCAD, long chain 3-hydroxyacyl-CoA dehydrogenase, long chain fatty acid oxidase, long-chain 3-hydroxy-acyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, long-chain 3-hydroxyacyl-CoA dehydrogenase, long-chain L-3 hydroxyacyl-CoA dehydrogenase, mitochondrial trifunctional protein, More, MTP |
| EC Number | 1.1.1.211 |
| CAS Registry Number | 84177-52-6 |
| Comments | This enzyme was purified from the mitochondrial inner membrane. The enzyme has a preference for long-chain substrates, and activity with C16 substrates was 6- to 15-fold higher than with C4 substrates. (cf. EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase). |
| Cofactor | |
| History | |
| Reactions | A long-chain (S)-3-hydroxyacyl-CoA + NAD(+) = a long-chain 3-oxoacyl-CoA + Nadh. |
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