long-chain-acyl-CoA-trehalose acyltransferase EC#: 2.3.1.279; ChemWhat Code: 1377116
Product Name | long-chain-acyl-CoA-trehalose acyltransferase |
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Synonyms | papA3 |
EC Number | 2.3.1.279 |
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Comments | The enzyme, characterized from the bacterium Mycobacterium tuberculosis, participates in the biosynthesis of polyacyltrehalose (PAT), a pentaacylated, trehalose-based glycolipid found in the cell wall of pathogenic strains. The enzyme catalyses two successive activities – it first transfers an acyl (often palmitoyl) group to position 2, followed by the transfer of a mycolipenyl group to position 3 (see EC 2.3.1.278, mycolipenoyl-CoA¡ª2-(long-chain-fatty acyl)-trehalose mycolipenoyltransferase). |
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