macrocin O-methyltransferase EC#: 2.1.1.101; ChemWhat Code: 1376280

Product Name macrocin O-methyltransferase
Example Structure Example Structure of macrocin O-methyltransferase EC#: 2.1.1.101
Synonyms macrocin methyltransferase, S-adenosyl-L-methionine-macrocin O-methyltransferase
EC Number 2.1.1.101
CAS Registry Number 79468-52-3
Comments Requires Mg2+, Mn2+ or Co2+. The 3-hydroxy group of a 2-O-methyl-6-deoxy-D-allose residue in the macrolide antibiotic macrosin acts as methyl acceptor. Isolated from Streptomyces fradiae. Tylosin is a macrolide antibiotic. Not identical with EC 2.1.1.102, demethylmacrocin O-methyltransferase.
Cofactor Mg2+
History
Reactions S-adenosyl-L-methionine + macrocin = S-adenosyl-L-homocysteine + tylosin.

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